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Bruker High Performance Bioscope Resolve Life Science Imaging System
Key Applications
- Enables users to increase the power of their research by complementing Contrast Enhancing techniques and Flourescence microscopy techniques
- Visualizes and measures native biological structures (no staining and/or coating required)
- Can be used as an ultrasensitive force sensor capable of detecting single ligand-receptor unbinding events
Key Features
- Closed-loop, "sample scanning" design wherein the AFM probe moves in the Z axis and the sample is scanned in the X & Y axis
- Temperature control up to 40 degrees Celsius while imaging and up to 60 degrees Celsius for sample processing
- Compatible with microscope slides, cover slips, plastic petri dishes (60 and 35 mm), and glass bottom petri dishes (50 mm)
Published Examples of AFM's Utility in the Biosciences
- DNA, protein, and chromatin structures
- Enzyme/substrate interactions
- Protein/Protein, protein/DNA interactions
- Adsorption properties of cells and molecules to biological or other surfaces
- Macromolecular assemblies
- Cell surface antigens
- Cellular and molecular interactions
- Antigen/antibody complexes
- Cell morphology and motility
Watch a video tutorial about the instrument!
