Come to NIFTI and experience Veeco’s BioScope II atomic force microscope, our latest addition to the facility. Gajendra Shekhawat, Research Assistant Professor and NIFTI facility manager, offers training and support. Sign up on NUANCE’s FOM system soon.

You will find that the BioScope—

• enables AFM imaging under a broad range of dynamic and biologically relevant conditions
• is easy to use with inverted optical microscopes, including confocal and TIRF systems
• integrates with optical techniques such as transmitted light - brightfield, darkfield, phase contrast, DIC, epifluorescence, FRAP and FRET.

The controller enables high pixel density imaging capabilities (5120 x 5120 pixels). Eight independent data channels allow simultaneous acquisition of multiple sample properties, and the BioScope II offers a Z range greater than 15µm and an X-Y range that exceeds 150 µm.

Full Top-Down Optical Access

Allows the use of commercially available Bright-field, DIC and Phase Contrast condensers up to 0.55 NA

Standard 850µm Wavelength IR Laser for Deflection Detection & Easy Fluid Operation

Compatible with 60mm Petri dishes

• Maintains live cell sample over long periods while imaging. This facilitates the imaging of long time scale dynamic processes.
• Provides the ability to control the chemical and liquid environment of the sample while imaging dynamic processes, such as self-assembly.

Benefits

• Spatial identification and mapping of protein molecules and cellular structures
• Optical guiding imaging of cell surfaces using transmitted light microscopy
• In-situ pharmacological studies of live cells
• Confocal and fluorescent imaging capabilities
• Cell response to mechanical response